Sepsis Definitions, Pathophysiology and the Challenge of Bedside Management

Sepsis is a disease syndrome that is difficult to understand as well as to treat and has
plagued mankind for thousands of years. In this textbook, the editors and authors
sought to assemble relatively brief but detailed compilations of what is the state of
the science on a variety of key topics. We have chosen topics that range from molecular
biology to clinical practice. It is our hope that this text can be used by bench
scientists and clinicians alike as a reference to aid in their work. Clinicians can learn
more about the biology behind the disease they treat and scientists can gain deeper
understanding into how the disease they study plays out in intensive care unit.
Together the clinical and scientific elements of this text will hopefully make a reference
that is of great value. We have picked as authors those who we feel are leaders
in the field they have written about and thus can provide vast experience as well as
data from years of study and practice.